Sure compounds present in grapefruit are recognized to inhibit CYP450 3A4 and may boost the bioavailability of swallowed fentanyl (reportedly around 75% of the dose) and
Any time you see a purple 8 while in the counting window, the bottle is finished and you will no longer be capable of get a full spray from it.
you have liver or kidney complications. It is because it could have an affect on the way through which Your whole body breaks down the drugs.
The company that markets PecFent will present instructional components in Just about every EU Member Point out to make sure that individuals, doctors and pharmacists are aware of how PecFent ought to be utilised, the potential risk of accidental publicity to fentanyl and the way to dispose of the medicine.
Ces effets pourraient être aussi bien indirects et imputables à une carence en soins maternels et/ou à une diminution du taux de lactation que la résultante d'un effet immediate du fentanyl sur la progéniture.
PecFent is often a ‘hybrid medicine’. Which means it is comparable to ‘reference medicines’ made up of the same active substance, but offered in a special way.
You must maintain PecFent in the child resistant storage container when you're not making use of it, even Should you have utilised all eight sprays. It is because PecFent might be lifetime-threatening if taken by a child by accident.
Opioid analgesics impair the psychological and/or Actual physical means needed for the effectiveness of probably perilous responsibilities (e.g.
PecFent is a medication useful for the management of breakthrough discomfort in Older people with most cancers who're now obtaining opioid therapy.
In the event you overlook a dose, acquire it as soon as you bear in mind. If It can be almost time for the following dose, skip the skipped dose and continue together with your standard agenda.
In case of overdose, patients ought to receive naloxone or nalmefene to reverse the action of the opioids as well as supportive measures to take care of the airway or advanced life aid in the situation of cardiac arrest.
Long-term pulmonary ailment: PecFent ought to be titrated with warning in patients with Long-term obstructive pulmonary ailment or pre-existing clinical problems predisposing them to respiratory depression.
PecFent is employed for the management of breakthrough suffering in sufferers with cancer who will be by now getting and who will be tolerant to opioid therapy read more for their fundamental persistent cancer soreness.
you happen to be allergic to fentanyl or any of another ingredients of the medicine (mentioned in Area 6).